Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689340 | 0.88 | LMNA (0.43) | MAP1LC3BLMNAALDH1A1HPGDALPL | |
| SCHEMBL7682795 | 0.88 | ALPL (0.51) | MAP1LC3BLMNAALDH1A1HPGDALPL | |
| SCHEMBL7685368 | 0.88 | LMNA (0.58) | MAP1LC3BLMNAALDH1A1HPGDHSP90AA1 | |
| SCHEMBL7681306 | 0.86 | ALDH1A1 (0.44) | MAP1LC3BLMNAALDH1A1HPGDMAOB | |
| SCHEMBL7689326 | 0.81 | GRM7 (0.42) | LMNAALDH1A1HPGDMAOBHSD17B10 | |
| SCHEMBL7681124 | 0.78 | MAP1LC3B (0.42) | MAP1LC3BLMNAALDH1A1HPGDUSP2 | |
| SCHEMBL7687762 | 0.77 | POLB (0.50) | MAP1LC3BLMNAALDH1A1HPGDMAPK1 | |
| SCHEMBL7689174 | 0.75 | LDHA (0.40) | MAP1LC3BLMNAALDH1A1USP2 | |
| SCHEMBL7678724 | 0.75 | LMNA (0.34) | LMNAALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL7683976 | 0.74 | MAP1LC3B (0.41) | MAP1LC3BLMNAALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |