Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684910 | 0.84 | MEN1 (0.34) | MEN1ALDH1A1KMT2AMMP13 | |
| SCHEMBL7687312 | 0.81 | ALDH1A1 (0.33) | PNMTMEN1ALDH1A1KMT2A | |
| SCHEMBL3198080 | 0.79 | ALDH1A1 (0.44) | MEN1ALDH1A1KMT2AMMP13PSIP1 | |
| SCHEMBL778104 | 0.78 | PSIP1 (0.54) | ALDH1A1KMT2APSIP1HSD11B1 | |
| SCHEMBL776676 | 0.77 | ALDH1A1 (0.43) | PNMTMEN1ALDH1A1KMT2AMMP13 | |
| SCHEMBL23501536 | 0.75 | GAA (0.55) | PNMTMEN1ALDH1A1KMT2AMMP13 | |
| SCHEMBL8795743 | 0.75 | CA2 (0.52) | PNMTMEN1ALDH1A1KMT2AMMP1 | |
| SCHEMBL3109115 | 0.75 | PLCG1 (0.59) | PNMTMEN1ALDH1A1KMT2AMMP13 | |
| SCHEMBL159760 | 0.73 | PSIP1 (0.58) | MEN1ALDH1A1KMT2APSIP1PLCG1 | |
| SCHEMBL9303097 | 0.72 | PNMT (0.44) | PNMTMEN1ALDH1A1KMT2AMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013171729-A2 | ARYL AND HETEROARYL AMIDE COMPOUNDS AS RORGAMAT MODULATOR | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-11-21 | — | — | WO | disclosed |
| WO-2012028100-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
| US-6362206-B1 | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-6034248-A | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-03-07 | — | — | US | disclosed |
| EP-0884311-A2 | Triazole Derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5792780-A | FUNGICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0657449-B1 | Azole compounds, their production and use as antifungal agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| US-5545652-A | Triazole and imidazole compounds and their use as antifungal therapeutic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-08-13 | — | — | US | disclosed |
| EP-0657449-A1 | Azole compounds, their production and use as antifungal agents | Takeda Chemical Industries, Ltd. (JP) | 1995-06-14 | — | — | EP | disclosed |
| EP-0097270-A1 | Organophosphate derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-01-04 | — | — | EP | disclosed |