Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.63 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.62 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.55 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040376 | 0.87 | GPR35 (0.73) | GPR35PIN1SMAD3EIF4A3KDM4E | |
| SCHEMBL22747199 | 0.85 | GPR35 (0.56) | GPR35PIN1SMAD3EIF4A3KDM4E | |
| SCHEMBL7092509 | 0.85 | GPR35 (0.56) | GPR35PIN1SMAD3EIF4A3KDM4E | |
| SCHEMBL17429451 | 0.85 | EIF4A3 (0.65) | GPR35PIN1SMAD3EIF4A3KDM4E | |
| SCHEMBL765246 | 0.85 | EIF4A3 (0.60) | GPR35PIN1SMAD3EIF4A3KDM4E | |
| SCHEMBL3100380 | 0.83 | SRD5A2 (0.58) | GPR35PIN1SMAD3EIF4A3KDM4E | |
| SCHEMBL16090785 | 0.82 | MMP2 (0.44) | GPR35PIN1EIF4A3KDM4EHPGD | |
| SCHEMBL18332181 | 0.80 | APEX1 (0.51) | GPR35PIN1SMAD3EIF4A3KDM4E | |
| SCHEMBL12495305 | 0.80 | PIN1 (0.50) | GPR35PIN1SMAD3EIF4A3KDM4E | |
| SCHEMBL31359900 | 0.80 | PIN1 (0.50) | GPR35PIN1SMAD3EIF4A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827602-B2 | Mono- or di-substituted indole derivatives as dengue viral replication inhibitors | Janssen Pharmaceuticals, Inc. (US) | 2023-11-28 | — | — | US | disclosed |
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827602-B2 | Mono- or di-substituted indole derivatives as dengue viral replication inhibitors | IDO1, IDO2, IRF3 | GPR35 2740/4885PIN1 909/4885SMAD3 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.