Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CCR9 | P51686 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 5/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684876 | 0.86 | CCR2 (0.51) | GPR35CACNA1BPLA2G4ACCR2LTB4R | |
| SCHEMBL6703456 | 0.85 | GPR35 (0.51) | GPR35CCR9CCR2KDM4EALDH1A1 | |
| SCHEMBL7677750 | 0.85 | PLA2G4A (0.49) | GPR35CACNA1BCCR9PLA2G4ACCR2 | |
| SCHEMBL3958982 | 0.84 | CCR2 (0.56) | GPR35PLA2G4ACCR2LTB4RLTB4R2 | |
| SCHEMBL7677561 | 0.84 | GPR35 (0.44) | GPR35CACNA1BCCR9PLA2G4ACCR2 | |
| SCHEMBL7681815 | 0.84 | CCR2 (0.55) | CACNA1BCCR9PLA2G4ACCR2LTB4R | |
| SCHEMBL7684727 | 0.83 | F10 (0.46) | CACNA1BLTB4RLTB4R2KDM4EALDH1A1 | |
| SCHEMBL7679772 | 0.82 | ACSS2 (0.45) | CACNA1BPLA2G4ACCR2LTB4RLTB4R2 | |
| SCHEMBL7683854 | 0.81 | CACNA1B (0.39) | GPR35CACNA1BCCR9CCR2KDM4E | |
| SCHEMBL7684946 | 0.80 | NTRK1 (0.52) | GPR35CACNA1BCCR9PLA2G4ACCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |