Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CCR9 | P51686 | 4/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684301 | 0.84 | KMT2A (0.42) | NTRK1ALDH1A1KDM4ELTB4RLTB4R2 | |
| SCHEMBL3958982 | 0.82 | CCR2 (0.56) | ALDH1A1KDM4EPLA2G4ACCR2GPR35 | |
| SCHEMBL7682472 | 0.80 | GPR35 (0.48) | ALDH1A1KDM4ECCR9PLA2G4ACACNA1B | |
| SCHEMBL7684876 | 0.79 | CCR2 (0.51) | ALDH1A1KDM4EPLA2G4ACACNA1BCCR2 | |
| SCHEMBL7677750 | 0.78 | PLA2G4A (0.49) | CCR9PLA2G4ACACNA1BCCR2GPR35 | |
| SCHEMBL7681815 | 0.77 | CCR2 (0.55) | NTRK1CCR9PLA2G4ACACNA1BCCR2 | |
| SCHEMBL7677561 | 0.77 | GPR35 (0.44) | ALDH1A1KDM4ECCR9PLA2G4ACACNA1B | |
| SCHEMBL7688499 | 0.76 | CCR9 (0.43) | ALDH1A1KDM4ECCR9PLA2G4ACACNA1B | |
| SCHEMBL2051739 | 0.76 | NTRK1 (0.64) | NTRK1ALDH1A1KDM4ECCR2CYP1A2 | |
| SCHEMBL7686579 | 0.76 | KDM4E (0.44) | NTRK1ALDH1A1KDM4ECCR9PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |