Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680997 | 0.87 | HTR2C (0.41) | MAP1LC3BALOX15TSHRHSD17B10HCAR2 | |
| SCHEMBL7678959 | 0.84 | SMN1; SMN2 (0.49) | MAP1LC3BALOX15TSHRHSD17B10HCAR2 | |
| SCHEMBL7685234 | 0.80 | ALOX15 (0.56) | MAP1LC3BALOX15TSHRHSD17B10KMT2A | |
| SCHEMBL7683976 | 0.73 | MAP1LC3B (0.41) | MAP1LC3BALOX15TSHRHSD17B10KMT2A | |
| SCHEMBL7689215 | 0.73 | TSHR (0.55) | MAP1LC3BTSHRHSD17B10HCAR2KMT2A | |
| SCHEMBL7680811 | 0.72 | — | — | |
| SCHEMBL27550390 | 0.72 | ALDH1A1 (0.33) | MAP1LC3BHCAR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7689622 | 0.71 | HSP90AA1 (0.41) | MAP1LC3BALOX15TSHRHSD17B10KMT2A | |
| SCHEMBL425265 | 0.69 | KDM1A (0.50) | MAP1LC3BHCAR2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7689197 | 0.69 | MAP1LC3B (0.36) | MAP1LC3BKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |