Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689340 | 0.84 | LMNA (0.43) | MAP1LC3BLMNAKDM1AALDH1A1HPGD | |
| SCHEMBL7685368 | 0.84 | LMNA (0.58) | MAP1LC3BLMNAALDH1A1HPGDTSHR | |
| SCHEMBL7683472 | 0.78 | MAP1LC3B (0.47) | MAP1LC3BLMNAALDH1A1HPGDTSHR | |
| SCHEMBL7683611 | 0.76 | MAP1LC3B (0.49) | MAP1LC3BLMNAKDM1AALDH1A1HPGD | |
| SCHEMBL7682795 | 0.76 | ALPL (0.51) | MAP1LC3BLMNAKDM1AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7685595 | 0.75 | KDM1A (0.34) | MAP1LC3BKDM1ATSHR | |
| SCHEMBL7689174 | 0.75 | LDHA (0.40) | MAP1LC3BLMNAALDH1A1 | |
| SCHEMBL7681124 | 0.74 | MAP1LC3B (0.42) | MAP1LC3BLMNAALDH1A1HPGDKDM4E | |
| SCHEMBL7687762 | 0.73 | POLB (0.50) | MAP1LC3BLMNAALDH1A1HPGDPOLB | |
| SCHEMBL7689326 | 0.72 | GRM7 (0.42) | LMNAALDH1A1HPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |