Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676299 | 0.92 | TSHR (0.34) | PTGS2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL7681363 | 0.90 | PTGS2 (0.41) | PTGS2ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL7685116 | 0.90 | ALDH1A1 (0.34) | ALDH1A1HSD17B10GAAPDE4APDE4B | |
| SCHEMBL7686030 | 0.86 | PTGS2 (0.35) | PTGS2ALDH1A1KDM4EHSD17B10PDE4A | |
| SCHEMBL7676272 | 0.85 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10PDE4APDE4B | |
| SCHEMBL7678830 | 0.84 | PDE4A (0.33) | ALDH1A1HSD17B10GAAPDE4APDE4B | |
| SCHEMBL7675255 | 0.83 | CNR1 (0.40) | POLB | |
| SCHEMBL7677645 | 0.82 | PTGS2 (0.40) | PTGS2ALDH1A1KDM4EPDE4APDE4B | |
| SCHEMBL7677560 | 0.80 | GRM5 (0.35) | ALDH1A1KDM4EHSD17B10GAAPDE4A | |
| SCHEMBL7679361 | 0.80 | PDE4B (0.38) | PTGS2ALDH1A1HSD17B10GAAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |