Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676299 | 0.94 | TSHR (0.34) | ALDH1A1POLBHPGDHSD17B10KMT2A | |
| SCHEMBL7683318 | 0.90 | PTGS2 (0.35) | ALDH1A1POLBHPGDHSD17B10KMT2A | |
| SCHEMBL7679361 | 0.88 | PDE4B (0.38) | ALDH1A1POLBHPGDHSD17B10KMT2A | |
| SCHEMBL7676272 | 0.87 | ALDH1A1 (0.35) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL7678830 | 0.86 | PDE4A (0.33) | ALDH1A1HPGDHSD17B10KMT2AGAA | |
| SCHEMBL7675255 | 0.86 | CNR1 (0.40) | POLBPTGESMAPK14 | |
| SCHEMBL7679294 | 0.85 | ALDH1A1 (0.34) | ALDH1A1POLBHPGDHSD17B10KMT2A | |
| SCHEMBL7677560 | 0.85 | GRM5 (0.35) | ALDH1A1HPGDHSD17B10KMT2AGAA | |
| SCHEMBL7677645 | 0.83 | PTGS2 (0.40) | ALDH1A1POLBHPGDKMT2AMEN1 | |
| SCHEMBL7684169 | 0.81 | ALDH1A1 (0.37) | ALDH1A1POLBHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |