Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679361 | 0.94 | PDE4B (0.38) | PTGS2LCKHPGDPDE4APDE4B | |
| SCHEMBL7681363 | 0.93 | PTGS2 (0.41) | PTGS2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7676299 | 0.89 | TSHR (0.34) | PTGS2LCKHPGDMAPTTP53 | |
| SCHEMBL7677586 | 0.86 | HTT (0.41) | PTGS2LCKHPGDPDE4APDE4B | |
| SCHEMBL7677539 | 0.86 | HPGD (0.39) | PTGS2HPGDPDE4APDE4BPDE4C | |
| SCHEMBL7683343 | 0.84 | PDE4B (0.39) | PTGS2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7677655 | 0.84 | CNR2 (0.40) | PTGS2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7682738 | 0.83 | ALDH1A1 (0.37) | HPGDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7685116 | 0.83 | ALDH1A1 (0.34) | HPGDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7683318 | 0.82 | PTGS2 (0.35) | PTGS2HPGDPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |