Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 5/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683727 | 0.87 | NOD2 (0.46) | MEN1KMT2ANOD2NOD1CCR2 | |
| SCHEMBL6701629 | 0.82 | MCL1 (0.50) | MCL1MEN1KMT2ADAONOD2 | |
| SCHEMBL11158786 | 0.79 | CNR2 (0.45) | MEN1KMT2ANOD2NOD1CNR2 | |
| SCHEMBL19347267 | 0.75 | CNR2 (0.46) | MEN1KMT2ACNR2TSHRKDM4E | |
| SCHEMBL7686433 | 0.73 | MAPT (0.44) | MEN1KMT2ANOD2NOD1ALDH1A1 | |
| SCHEMBL5823619 | 0.72 | MCL1 (0.62) | MCL1DAOCCR2ALDH1A1TSHR | |
| SCHEMBL9092058 | 0.71 | KDM4E (0.54) | KMT2ACNR2ALDH1A1TSHRKDM4E | |
| SCHEMBL7684555 | 0.71 | MCL1 (0.53) | MCL1MEN1KMT2ADAOCCR2 | |
| SCHEMBL5794123 | 0.71 | NOD2 (0.57) | MEN1KMT2ANOD2NOD1ALDH1A1 | |
| SCHEMBL29463237 | 0.71 | NOD2 (0.57) | MEN1KMT2ANOD2NOD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |