Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.42 |
| ▸ | MMP9 | P14780 | 9/20 | 0.42 |
| ▸ | MMP13 | P45452 | 7/20 | 0.42 |
| ▸ | MMP3 | P08254 | 5/20 | 0.42 |
| ▸ | MMP1 | P03956 | 4/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685476 | 0.92 | MMP2 (0.42) | MMP2MMP9MMP13MMP3MAPT | |
| SCHEMBL7679666 | 0.91 | MMP9 (0.43) | MMP2MMP9MMP13MMP3MMP1 | |
| SCHEMBL7686355 | 0.90 | MMP9 (0.44) | MMP2MMP9MMP13MMP8CNR2 | |
| SCHEMBL7683595 | 0.90 | MMP2 (0.44) | MMP2MMP9MMP13MMP3MMP1 | |
| SCHEMBL7678024 | 0.90 | CNR2 (0.40) | MMP2MMP9MMP13MMP8LMNA | |
| SCHEMBL7680424 | 0.90 | MMP13 (0.45) | MMP2MMP9MMP13MMP3MMP8 | |
| SCHEMBL7686256 | 0.90 | MMP9 (0.40) | MMP2MMP9MMP13MMP3MMP1 | |
| SCHEMBL7686108 | 0.89 | MMP2 (0.42) | MMP2MMP9MMP13MMP3MMP1 | |
| SCHEMBL7687017 | 0.89 | MMP2 (0.39) | MMP2MMP9MMP13MMP8LMNA | |
| SCHEMBL7682261 | 0.89 | ALDH1A1 (0.37) | MMP2MMP9MMP13MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | claimed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | claimed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |