Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682401 | 0.85 | CHRNB2 (0.32) | — | |
| SCHEMBL7688677 | 0.84 | KCNH2 (0.35) | OPRK1KCNH2RETOPRL1OPRM1 | |
| SCHEMBL7685772 | 0.81 | KCNH2 (0.37) | OPRK1KCNH2RETOPRL1OPRM1 | |
| SCHEMBL7687764 | 0.79 | OPRK1 (0.35) | OPRK1KCNH2RET | |
| SCHEMBL7221508 | 0.79 | OPRL1 (0.43) | OPRK1KCNH2RETOPRL1OPRM1 | |
| SCHEMBL7690952 | 0.77 | KCNH2 (0.33) | OPRK1KCNH2OPRM1 | |
| SCHEMBL7685312 | 0.77 | OPRL1 (0.39) | OPRK1KCNH2RETOPRL1OPRM1 | |
| SCHEMBL6615999 | 0.75 | OPRM1 (0.39) | OPRK1KCNH2OPRL1OPRM1 | |
| SCHEMBL7686091 | 0.74 | CHRNB2 (0.30) | — | |
| SCHEMBL7688348 | 0.73 | CHRM2 (0.36) | OPRK1KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020061913-A1 | Bicyclic amine derivatives | SYNGENTA LIMITED (GB) | 2002-05-23 | — | — | US | disclosed |
| US-6291474-B1 | COMBATING AND CONTROLLING INSECT, ACARINE OR NEMATODE PESTS | ZENECA LIMITED (GB) | 2001-09-18 | — | — | US | disclosed |
| US-6177442-B1 | INSECTICIDES; PESTICIDES; MITICIDES; NEMATOCIDES | ZENECA LIMITED (GB) | 2001-01-23 | — | — | US | disclosed |
| EP-1033914-A1 | BICYCLIC AMINES AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 2000-09-13 | — | — | EP | disclosed |
| US-5968947-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1999-10-19 | — | — | US | disclosed |
| WO-1999026478-A1 | BICYCLIC AMINES AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 1999-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061913-A1 | Bicyclic amine derivatives | ADRA1D, TAAR1, ADRA1A | OPRK1 523/4885KCNH2 1046/4885RET 2615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.