Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | AOC2 | O75106 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686580 | 0.92 | ACHE (0.33) | ACHEHRH3CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL7681879 | 0.92 | CYP2D6 (0.38) | ACHEHRH3CYP2D6CHRM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7684461 | 0.91 | CYP2D6 (0.38) | ACHEHRH3CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL7680314 | 0.89 | ACHE (0.37) | ACHEHRH3CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL7680673 | 0.89 | GPR119 (0.35) | ACHEHRH3CYP2D6CHRM2ALDH1A1 | |
| SCHEMBL7680487 | 0.87 | RAB9A (0.35) | ACHEHRH3CYP2D6ALDH1A1KDM4E | |
| SCHEMBL7676228 | 0.83 | CYP2D6 (0.40) | ACHEHRH3CYP2D6CHRM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7685406 | 0.82 | RBP4 (0.31) | HRH3CHRM2MAPTSMN1; SMN2CHRM1 | |
| SCHEMBL7687050 | 0.81 | CYP2D6 (0.41) | ACHEHRH3CYP2D6CHRM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7686863 | 0.81 | CYP2D6 (0.38) | ACHEHRH3CYP2D6CHRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472397-B1 | Nitrogen-containing heterocyclic compounds having antiplatelet aggregation effect and medicinal use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 2002-10-29 | — | — | US | disclosed |
| EP-1070712-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS HAVING ANTIPLATELET AGGREGATION EFFECT AND MEDICINAL USE THEREOF | MEIJI SEIKA KAISHA LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |