Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7688076 | 0.99 | LMNA (0.53) | OPRD1OPRK1LMNAKDM4ELDHA | |
| SCHEMBL7682400 | 0.87 | LDHA (0.58) | OPRD1OPRK1KDM4ELDHATSHR | |
| SCHEMBL1478245 | 0.80 | EPHX2 (0.48) | OPRK1KDM4ETSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL6778533 | 0.78 | LMNA (0.55) | LMNAKDM4ELDHASMN1; SMN2ATM | |
| SCHEMBL9008064 | 0.77 | LDHA (0.54) | LMNALDHASMN1; SMN2CA12CA1 | |
| SCHEMBL491026 | 0.76 | LDHA (0.71) | LMNALDHASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL20382349 | 0.75 | ALDH1A1 (0.48) | OPRD1OPRK1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7684481 | 0.74 | SIGMAR1 (0.56) | LMNAKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL20382390 | 0.73 | KDM4E (0.47) | OPRD1OPRK1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL7296827 | 0.73 | LDHA (0.59) | LMNALDHASMN1; SMN2ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492522-B1 | OPTICAL ISOMERS AND SALTS WITH 4-PYRIDINECARBOXALDEHYDE IN THE PRESENCE OF BASE TO GIVE A COMPOUND OF THE FORMULA REACTING THE COMPOUND OBTAINED IN STEP B) ABOVE OR A SALT THEREOF WITH A COMPOUND OF FORMULA R.SUP.10 X, WHEREIN R.SUP.10, | FINETECH LABORATORIES LTD. (IL) | 2002-12-10 | — | — | US | disclosed |
| EP-1129073-A2 | PROCESS AND INTERMEDIATES FOR PRODUCTION OF DONEPEZIL AND RELATED COMPOUNDS | Finetech Ltd (IL) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000009483-A2 | PROCESS AND INTERMEDIATES FOR PRODUCTION OF DONEPEZIL AND RELATED COMPOUNDS | FINETECH LTD. (IL) | 2000-02-24 | — | — | WO | disclosed |