Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12252425 | 0.85 | KMT2A (0.54) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL6432262 | 0.84 | P2RY6 (0.50) | KMT2AP2RY6HDAC1HDAC6MAPT | |
| SCHEMBL14579478 | 0.84 | KDM4E (0.58) | P2RY6HDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL8575469 | 0.83 | P2RY6 (0.47) | KMT2AP2RY6HSD17B10TPSAB1PRSS1 | |
| SCHEMBL12133623 | 0.80 | KMT2A (0.76) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL8603312 | 0.80 | P2RY6 (0.47) | KMT2AP2RY6HSD17B10TPSAB1PRSS1 | |
| SCHEMBL343680 | 0.79 | GAA (0.49) | P2RY6HDAC1HDAC6MAPTRAB9A | |
| SCHEMBL16190422 | 0.79 | KMT2A (0.59) | KMT2AHDAC1HDAC6MAPTALDH1A1 | |
| SCHEMBL8575681 | 0.78 | MCL1 (0.60) | P2RY6HSD17B10TPSAB1PRSS1CHRM1 | |
| SCHEMBL8578080 | 0.78 | P2RY6 (0.42) | KMT2AP2RY6ALDH1A1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649253-B2 | Terbium and dysprosium complexes with optimised antenna, used as luminescent markers | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2023-05-16 | — | — | US | disclosed |
| US-9920082-B2 | Water-soluble complexing agents and corresponding lanthanide complexes | CISBO BIOASSAYS (FR) | 2018-03-20 | — | — | US | disclosed |
| US-9296762-B2 | Complexing agents and corresponding lanthanide complexes | CISBIO BIOASSAYS (FR) | 2016-03-29 | — | — | US | disclosed |
| US-20160031910-A1 | LANTHANIDE COMPLEXES COMPRISING AT LEAST TWO BETAINE GROUPS, WHICH CAN BE USED AS LUMINESCENT MARKERS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2016-02-04 | — | — | US | disclosed |
| US-20150361116-A1 | NOVEL WATER-SOLUBLE COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES | CISBIO BIOASSAYS (FR) | 2015-12-17 | — | — | US | disclosed |
| US-9024022-B2 | Substrates of O6-alkylguanine-DNA alkyltransferase and mutants thereof | CIS BIO INTERNATIONAL (FR) | 2015-05-05 | — | — | US | disclosed |
| US-20140336373-A1 | NOVEL COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES | CISBIO BIOASSAYS (FR) | 2014-11-13 | — | — | US | disclosed |
| US-20110236952-A1 | NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF | CIS BIO INTERNATIONAL (FR) | 2011-09-29 | — | — | US | disclosed |
| US-20020028469-A1 | Method of defining genus of chemical compound and method of designing molecules | BURCH RONALD M (US) | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110236952-A1 | NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF | OGG1, UNG, MPG | KMT2A 707/4885P2RY6 3755/4885HDAC1 1945/4885 |
| US-20150361116-A1 | NOVEL WATER-SOLUBLE COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES | RCC1, CLIC1, RCC2 | KMT2A 3944/4885P2RY6 4304/4885HDAC1 2380/4885 |
| US-11649253-B2 | Terbium and dysprosium complexes with optimised antenna, used as luminescent markers | SSB, TACR3, MAL2 | KMT2A 4741/4885P2RY6 3453/4885HDAC1 3079/4885 |
| US-20160031910-A1 | LANTHANIDE COMPLEXES COMPRISING AT LEAST TWO BETAINE GROUPS, WHICH CAN BE USED AS LUMINESCENT MARKERS | SLC6A12, LGALS3, LBR | KMT2A 4325/4885P2RY6 2895/4885HDAC1 3184/4885 |
| US-20140336373-A1 | NOVEL COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES | RCC1, RCC2, C1R | KMT2A 3629/4885P2RY6 3667/4885HDAC1 666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.