Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.57 |
| ▸ | MMP13 | P45452 | 4/20 | 0.57 |
| ▸ | MMP9 | P14780 | 3/20 | 0.57 |
| ▸ | MMP1 | P03956 | 2/20 | 0.57 |
| ▸ | MMP8 | P22894 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MEP1B | Q16820 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEP1A | Q16819 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BMP1 | P13497 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7918690 | 0.82 | CA1 (0.60) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL2845552 | 0.81 | MEP1B (0.68) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL8041132 | 0.78 | BMP1 (0.58) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL6411529 | 0.76 | BMP1 (0.53) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL7325418 | 0.75 | ALDH1A1 (0.55) | CA2ALDH1A1POLBSMN1; SMN2ESR1 | |
| SCHEMBL7338644 | 0.75 | MEP1B (0.81) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL19474705 | 0.74 | MEP1B (0.74) | CA1CA2MEP1BMEP1A | |
| SCHEMBL13899083 | 0.72 | MMP2 (0.67) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL4674829 | 0.71 | CA1 (0.49) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL14460020 | 0.71 | GAA (0.70) | ALDH1A1POLBSMN1; SMN2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495358-B1 | OPEN SULFAMIDE STRUCTURE IS ANTICIPATED TO BE MORE STABLE CHEMICALLY THAN RELATED CLOSED RING STRUCTURES; SERINE AND CYSTEINE PROTEASES | WICHITA STATE UNIVERSITY | 2002-12-17 | — | — | US | disclosed |