Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD5 | P21918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687809 | 0.88 | AR (0.33) | AR | |
| SCHEMBL7694251 | 0.83 | HSP90AA1 (0.31) | HSP90AA1HSP90AB1 | |
| SCHEMBL7689395 | 0.83 | HSP90AA1 (0.31) | ARHSP90AA1HSP90AB1 | |
| SCHEMBL7686734 | 0.81 | HSP90AB1 (0.49) | HSP90AA1HSP90AB1 | |
| SCHEMBL7811612 | 0.76 | AR (0.34) | AR | |
| SCHEMBL7694982 | 0.75 | PGK1 (0.40) | HSP90AA1HSP90AB1DRD1 | |
| SCHEMBL7968440 | 0.74 | — | — | |
| SCHEMBL7686737 | 0.72 | PDE10A (0.30) | — | |
| SCHEMBL7688339 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL7690605 | 0.71 | HSD11B1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339046-B1 | FOR CONTROLLING WEEDS | SYNGENTA INVESTMENT CORPORATION | 2002-01-15 | — | — | US | disclosed |
| EP-0839808-A1 | Pyrazole derivatives, processes for their preparation, and their use as herbicides | Novartis AG (CH) | 1998-05-06 | — | — | EP | disclosed |