Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.48 |
| ▸ | ITGAV | P06756 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686877 | 1.00 | CTRB1 (0.50) | CTRB1IDO1TDO2PPARGPPARA | |
| SCHEMBL7686873 | 1.00 | CTRB1 (0.50) | CTRB1IDO1TDO2PPARGPPARA | |
| SCHEMBL29205771 | 0.85 | ITGB3 (0.50) | IDO1TDO2ITGB3ITGAVITGA2B | |
| SCHEMBL26089886 | 0.84 | ITGB3 (0.58) | IDO1TDO2PPARGPPARACASP1 | |
| SCHEMBL26089884 | 0.84 | ITGB3 (0.58) | IDO1TDO2PPARGPPARACASP1 | |
| SCHEMBL8387978 | 0.82 | FOLH1 (0.65) | PPARGPPARAITGB3ITGAVITGA2B | |
| SCHEMBL10421088 | 0.82 | FOLH1 (0.62) | CTRB1IDO1TDO2PPARGPPARA | |
| SCHEMBL14125684 | 0.81 | CASP1 (0.60) | CASP1ITGB3ITGAVITGA2BCTSK | |
| SCHEMBL2487005 | 0.81 | CTSL (0.65) | PPARGPPARACASP1CTSKCTSL | |
| SCHEMBL1701581 | 0.81 | CTSL (0.65) | PPARGPPARACASP1CTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002055499-A1 | INTERMEDIATES FOR THE SYNTHESIS OF PYRIDINOLINE AND PREPARATION THEREOF | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2002-07-18 | — | — | WO | disclosed |