Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678044 | 0.79 | MEN1 (0.40) | CRHR1KMT2ASORT1PFKFB3MEN1 | |
| SCHEMBL7687220 | 0.77 | CRHR1 (0.34) | CRHR1SORT1PFKFB3COPS5EIF4A3 | |
| SCHEMBL7678167 | 0.76 | KDM4E (0.36) | CRHR1KMT2AKDM4EMEN1 | |
| SCHEMBL7680570 | 0.71 | SMN1; SMN2 (0.42) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL11431410 | 0.63 | AKR1C3 (0.45) | KMT2AMEN1 | |
| SCHEMBL27598611 | 0.62 | CRHR1 (0.39) | CRHR1NPC1RAB9A | |
| SCHEMBL12591789 | 0.61 | GAA (0.41) | CRHR1NPC1RAB9A | |
| SCHEMBL3884223 | 0.61 | TRPA1 (0.46) | NPC1RAB9A | |
| SCHEMBL12304013 | 0.60 | DHODH (0.44) | CRHR1CA12CA1CA2CA9 | |
| SCHEMBL5855306 | 0.60 | ALDH1A1 (0.44) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |