Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | IDH1 | O75874 | 3/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.33 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678044 | 0.81 | MEN1 (0.40) | CRHR1SORT1PFKFB3EIF4A3DHODH | |
| SCHEMBL7687217 | 0.77 | CRHR1 (0.33) | CRHR1SORT1PFKFB3EIF4A3COPS5 | |
| SCHEMBL7678171 | 0.74 | IDH1 (0.39) | CRHR1IDH1 | |
| SCHEMBL7680571 | 0.68 | RAB9A (0.43) | — | |
| SCHEMBL3189801 | 0.62 | LMNA (0.41) | CRHR1 | |
| SCHEMBL12304013 | 0.62 | DHODH (0.44) | CRHR1SORT1EIF4A3DHODH | |
| SCHEMBL24679021 | 0.59 | EIF4A3 (0.37) | EIF4A3DHODHCOPS5 | |
| SCHEMBL28271921 | 0.59 | POLB (0.50) | SORT1EIF4A3DHODH | |
| SCHEMBL1795934 | 0.58 | SMN1; SMN2 (0.41) | SORT1 | |
| SCHEMBL11852129 | 0.58 | FABP4 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |