Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.36 |
| ▸ | MAP2 | P11137 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 2/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693977 | 0.88 | MAPT (0.40) | MAPTTP53KDM4EALDH1A1SHMT2 | |
| SCHEMBL7487729 | 0.80 | MAPT (0.41) | MAPTTP53KDM4EALDH1A1SHMT2 | |
| SCHEMBL8035641 | 0.77 | HSP90AA1 (0.34) | ALDH1A1HTTPPOXHSP90AA1HSP90AB1 | |
| SCHEMBL7690601 | 0.76 | HSP90AB1 (0.39) | PPOXHSP90AA1HSP90AB1 | |
| SCHEMBL7692478 | 0.74 | GRM5 (0.40) | MAPTKDM4EALDH1A1SHMT2HTT | |
| SCHEMBL7687213 | 0.72 | HTR5A (0.38) | TGFBR1HTTKMT2A | |
| SCHEMBL5398257 | 0.72 | CYP1A2 (0.35) | MAPTHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL9530563 | 0.71 | PTGS2 (0.39) | MAPTTP53KDM4EALDH1A1NPC1 | |
| SCHEMBL6281955 | 0.71 | PPOX (0.37) | MAPTTP53ALDH1A1HTTHTR2A | |
| SCHEMBL7489274 | 0.70 | HSP90AB1 (0.38) | MAPTTP53ALDH1A1RAB9APPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339046-B1 | FOR CONTROLLING WEEDS | SYNGENTA INVESTMENT CORPORATION | 2002-01-15 | — | — | US | disclosed |
| EP-0839808-A1 | Pyrazole derivatives, processes for their preparation, and their use as herbicides | Novartis AG (CH) | 1998-05-06 | — | — | EP | disclosed |