Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031377 | 0.83 | PGK1 (0.38) | PGK1 | |
| SCHEMBL8021916 | 0.82 | DRD2 (0.32) | — | |
| SCHEMBL8022013 | 0.82 | POLB (0.32) | — | |
| SCHEMBL8021924 | 0.80 | GAA (0.36) | ALDH1A1NPSR1 | |
| SCHEMBL7690601 | 0.79 | HSP90AB1 (0.39) | HSP90AA1HSP90AB1MAPK10PDE10APDE2A | |
| SCHEMBL7687973 | 0.77 | MAPT (0.40) | HSP90AA1HSP90AB1ALDH1A1HTTPPOX | |
| SCHEMBL7693977 | 0.77 | MAPT (0.40) | HSP90AA1HSP90AB1ALDH1A1HTTNPSR1 | |
| SCHEMBL8031860 | 0.76 | HSD11B1 (0.40) | PDE2AMAPK14 | |
| SCHEMBL5398257 | 0.74 | CYP1A2 (0.35) | HSP90AA1HSP90AB1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8566536 | 0.74 | PDE10A (0.33) | HSP90AA1HSP90AB1CYP1A2PDE10APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103667-A | Phenylpyrazole herbicides | NOVARTIS CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0832070-A1 | NOVEL HERBICIDES | Novartis AG (CH) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997000246-A1 | NOVEL HERBICIDES | NOVARTIS AG (CH) | 1997-01-03 | — | — | WO | disclosed |