Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.52 |
| ▸ | F10 | P00742 | 4/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28099443 | 0.85 | KDM4E (0.65) | CNR2F10KDM4ECRHBPCRHR2 | |
| SCHEMBL7880746 | 0.83 | MTNR1A (0.62) | CNR2KDM4ECRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL8709627 | 0.82 | ALDH1A1 (0.60) | CNR2CCR2ALDH1A1CYP1A2POLB | |
| SCHEMBL25893621 | 0.81 | F10 (0.57) | F10F2SRCKDM4ECRHBP | |
| SCHEMBL7682421 | 0.80 | MTNR1A (0.51) | F10F2SRCKDM4ECRHBP | |
| SCHEMBL28111591 | 0.79 | KDM4E (0.63) | CNR2F10KDM4ECRHBPCRHR2 | |
| SCHEMBL22258127 | 0.78 | MCL1 (0.60) | F10F2SRCKMT2ANOD2 | |
| SCHEMBL6706252 | 0.78 | KMT2A (0.40) | F10KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7682048 | 0.77 | KMT2A (0.57) | F10F2SRCKDM4ECRHBP | |
| SCHEMBL8689867 | 0.77 | KDM4E (0.54) | CNR2F10F2SRCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |