Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27460658 | 0.75 | HDAC7 (0.67) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27592177 | 0.74 | BCAT2 (0.59) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12832621 | 0.74 | CHRNB2 (0.58) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27577620 | 0.73 | CHRNB2 (0.61) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6631304 | 0.73 | CHRNB2 (0.89) | GAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9532593 | 0.72 | GAA (0.59) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1670666 | 0.71 | KMT2A (0.67) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6711198 | 0.71 | GAA (0.76) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31517118 | 0.70 | HNF4A (0.61) | ALDH1A1MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL1479704 | 0.70 | HNF4A (0.61) | ALDH1A1MEN1KMT2ASMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080051386-A1 | Tricyclic Pyrazole Derivatives as Cannabinoid Receptor Modulators | CADILA HEALTHCARE LIMITED (IN) | 2008-02-28 | — | — | US | claimed |
| EP-1781668-A2 | TRICYCLIC PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CADILA HEALTHCARE LTD. (IN) | 2007-05-09 | — | — | EP | claimed |
| WO-2006025069-A2 | TRICYCLIC PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2006-03-09 | — | — | WO | claimed |
| US-20080051386-A1 | Tricyclic Pyrazole Derivatives as Cannabinoid Receptor Modulators | CADILA HEALTHCARE LIMITED (IN) | 2008-02-28 | — | — | US | disclosed |
| EP-1781668-A2 | TRICYCLIC PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CADILA HEALTHCARE LTD. (IN) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006025069-A2 | TRICYCLIC PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051386-A1 | Tricyclic Pyrazole Derivatives as Cannabinoid Receptor Modulators | CNR2, CNR1, GPR55 | GAA 4251/4885ALDH1A1 2966/4885MEN1 4219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.