Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.49 |
| ▸ | MMP12 | P39900 | 7/20 | 0.49 |
| ▸ | MMP9 | P14780 | 5/20 | 0.49 |
| ▸ | MMP1 | P03956 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684371 | 0.82 | RAB9A (0.60) | MMP2RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7681707 | 0.81 | ALDH1A1 (0.71) | MMP2MMP12MMP9MMP1RAB9A | |
| SCHEMBL7685975 | 0.79 | RAB9A (0.59) | MMP2MMP12MMP9MMP1RAB9A | |
| SCHEMBL22939050 | 0.76 | KMT2A (0.62) | MMP2MMP12MMP9MMP1RAB9A | |
| SCHEMBL6513604 | 0.76 | MMP2 (0.51) | MMP2MMP12MMP9MMP1RAB9A | |
| SCHEMBL3721413 | 0.75 | MMP2 (0.53) | MMP2MMP12MMP9MMP1RAB9A | |
| SCHEMBL30741601 | 0.75 | IDO1 (0.61) | MMP2MMP12MMP9MMP1RAB9A | |
| SCHEMBL3964905 | 0.75 | IDO1 (0.61) | MMP2MMP12MMP9MMP1RAB9A | |
| SCHEMBL6516931 | 0.75 | MMP1 (0.50) | MMP2MMP12MMP9MMP1RAB9A | |
| SCHEMBL22939052 | 0.74 | MMP2 (0.55) | MMP2MMP12MMP9MMP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |