SCHEMBL768987

SCHEMBL768987

CCCCC(CC)(CO)C(OP(=O)(O)O)c1c(C(C)(C)C)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR5A2 O00482 1/20 0.36
NR5A1 Q13285 1/20 0.36
RXRA P19793 2/20 0.33
PPARG P37231 2/20 0.33
S1PR1 P21453 10/20 0.32
S1PR3 Q99500 7/20 0.32
HMGCR P04035 2/20 0.32
S1PR4 O95977 4/20 0.31
S1PR5 Q9H228 3/20 0.31
S1PR2 O95136 3/20 0.31
PTPN1 P18031 1/20 0.31
SMPD1 P17405 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL769381 0.88 NR5A2 (0.31) NR5A2NR5A1
SCHEMBL10277106 0.84 S1PR1 (0.33) S1PR1S1PR3S1PR4S1PR5S1PR2
Phosphoric Acid SCHEMBL768989 0.82 NR5A2 (0.38) NR5A2NR5A1RXRAPPARG
SCHEMBL496750 0.81 NR5A2 (0.32) NR5A2NR5A1RXRAPPARG
SCHEMBL768988 0.78 NR5A2 (0.36) NR5A2NR5A1RXRAPPARGS1PR1
SCHEMBL3894057 0.78 NR5A2 (0.36) NR5A2NR5A1RXRAPPARG
SCHEMBL496787 0.75 NR5A2 (0.34) NR5A2NR5A1RXRAPPARG
SCHEMBL1032613 0.72 ALDH1A1 (0.30)
Pyrophosphoric Acid SCHEMBL3635254 0.71 RXRA (0.31) RXRAPPARG
SCHEMBL5461582 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3071544-A2 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME Polnox Corporation (US) 2016-09-28 EP claimed
WO-2015077635-A2 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION (US) 2015-05-28 WO claimed
EP-2523985-B1 CONCURRENT SOLID & MELT STATE GRAFTING OF COAGENTS FOR MAKING LONG CHAIN BRANCHED POLYPROPYLENE VIA DIRECT REACTIVE EXTRUSION PROCESS RELIANCE IND LTD (IN) 2015-03-11 EP claimed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US claimed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US claimed
US-20130072586-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2013-03-21 US claimed
US-20130059958-A1 CONCURRENT SOLID & MELT STATE GRAFTING OF COAGENTS FOR MAKING LONG CHAIN BRANCHED POLYPROPYLENE VIA DIRECT REACTIVE EXTRUSION PROCESS RELIANCE INDUSTRIES LIMITED (IN) 2013-03-07 US claimed
EP-2523985-A1 CONCURRENT SOLID & MELT STATE GRAFTING OF COAGENTS FOR MAKING LONG CHAIN BRANCHED POLYPROPYLENE VIA DIRECT REACTIVE EXTRUSION PROCESS Reliance Industries Limited (IN) 2012-11-21 EP claimed
US-8252884-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2012-08-28 US claimed
US-20120071596-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2012-03-22 US claimed
US-8008423-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2011-08-30 US claimed
WO-2011086581-A1 CONCURRENT SOLID & MELT STATE GRAFTING OF COAGENTS FOR MAKING LONG CHAIN BRANCHED POLYPROPYLENE VIA DIRECT REACTIVE EXTRUSION PROCESS RELIANCE INDUSTRIES LIMITED (IN) 2011-07-21 WO claimed
US-20100305251-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2010-12-02 US claimed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US claimed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US claimed
EP-1966293-A1 STABILIZED POLYOLEFIN COMPOSITIONS Polnox Corporation (US) 2008-09-10 EP claimed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US claimed
WO-2007050991-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION (US) 2007-05-03 WO claimed
US-6783160-B2 Plastic-lined metal-encased tubing segment connector system MERCURY PLASTICS, INC. 2004-08-31 US claimed
EP-3071544-B1 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME POLNOX CORP (US) 2022-07-06 EP disclosed
US-11060027-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same POLNOX CORPORATION (US) 2021-07-13 US disclosed
US-20200392406-A1 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2020-12-17 US disclosed
US-10683455-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same POLNOX CORPORATION (US) 2020-06-16 US disclosed
US-20190292454-A1 Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same POLNOX CORPORATION 2019-09-26 US disclosed
US-10294423-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same POLNOX CORPORATION (US) 2019-05-21 US disclosed
US-20160289558-A1 Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same POLNOX CORPORATION (US) 2016-10-06 US disclosed
EP-2961799-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITIONS Covestro LLC (US) 2016-01-06 EP disclosed
US-9145490-B2 Flame-retardant polycarbonate compositions BAYER MATERIALSCIENCE LLC (US) 2015-09-29 US disclosed
US-20150247024-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITIONS BAYER MATERIALSCIENCE LLC (US) 2015-09-03 US disclosed
EP-2523985-B1 CONCURRENT SOLID & MELT STATE GRAFTING OF COAGENTS FOR MAKING LONG CHAIN BRANCHED POLYPROPYLENE VIA DIRECT REACTIVE EXTRUSION PROCESS RELIANCE IND LTD (IN) 2015-03-11 EP disclosed
US-8921466-B2 Concurrent solid and melt state grafting of coagents for making long chain branched polypropylene via direct reactive extrusion process RELIANCE INDUSTRIES LIMITED (IN) 2014-12-30 US disclosed
WO-2014133933-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITIONS BAYER MATERIALSCIENCE LLC (US) 2014-09-04 WO disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-20130090419-A1 POLYCARBONATE COMPOSITIONS HAVING IMPROVED WATER RESISTANCE AND RELATED METHODS BAYER MATERIALSCIENCE LLC (US) 2013-04-11 US disclosed
US-20130072586-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2013-03-21 US disclosed
US-20130059958-A1 CONCURRENT SOLID & MELT STATE GRAFTING OF COAGENTS FOR MAKING LONG CHAIN BRANCHED POLYPROPYLENE VIA DIRECT REACTIVE EXTRUSION PROCESS RELIANCE INDUSTRIES LIMITED (IN) 2013-03-07 US disclosed
EP-2523985-A1 CONCURRENT SOLID & MELT STATE GRAFTING OF COAGENTS FOR MAKING LONG CHAIN BRANCHED POLYPROPYLENE VIA DIRECT REACTIVE EXTRUSION PROCESS Reliance Industries Limited (IN) 2012-11-21 EP disclosed
US-8287631-B2 Compounds for preventing ghost odour THOR GMBH (DE) 2012-10-16 US disclosed
US-8252884-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2012-08-28 US disclosed
US-20120071596-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2012-03-22 US disclosed
US-8008423-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2011-08-30 US disclosed
WO-2011086581-A1 CONCURRENT SOLID & MELT STATE GRAFTING OF COAGENTS FOR MAKING LONG CHAIN BRANCHED POLYPROPYLENE VIA DIRECT REACTIVE EXTRUSION PROCESS RELIANCE INDUSTRIES LIMITED (IN) 2011-07-21 WO disclosed
US-20100305251-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2010-12-02 US disclosed
US-20100186631-A1 Compounds for preventing ghost odour THOR GMBH (DE) 2010-07-29 US disclosed
US-20100151371-A1 IMAGING MEMBER XEROX CORPORATION (US) 2010-06-17 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
EP-1966293-A1 STABILIZED POLYOLEFIN COMPOSITIONS Polnox Corporation (US) 2008-09-10 EP disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
WO-2007050991-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION (US) 2007-05-03 WO disclosed
WO-2007050991-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION (US) 2007-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11060027-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same LPO, GPX4, DUOX2 NR5A2 3593/4885NR5A1 3377/4885RXRA 2388/4885
US-10683455-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same LPO, GPX4, DUOX2 NR5A2 3593/4885NR5A1 3377/4885RXRA 2388/4885
US-20160289558-A1 Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same LPO, GPX4, DUOX2 NR5A2 3878/4885NR5A1 3545/4885RXRA 2621/4885
US-20190292454-A1 Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same LPO, GPX4, DUOX2 NR5A2 3593/4885NR5A1 3377/4885RXRA 2388/4885
US-20200392406-A1 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME LPO, GPX4, DUOX2 NR5A2 3593/4885NR5A1 3377/4885RXRA 2388/4885
US-10294423-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same LPO, GPX4, DUOX2 NR5A2 3878/4885NR5A1 3545/4885RXRA 2621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.