Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | USP8 | P40818 | 1/20 | 0.34 |
| ▸ | USP7 | Q93009 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695108 | 0.81 | NPSR1 (0.39) | HSD11B1CRHR1SLC34A1PDE2AMEN1 | |
| SCHEMBL7690463 | 0.80 | TGFBR1 (0.34) | PDE2AMEN1KMT2ANPSR1TDP1 | |
| SCHEMBL7686737 | 0.79 | PDE10A (0.30) | — | |
| SCHEMBL7688339 | 0.79 | LMNA (0.32) | — | |
| SCHEMBL7687809 | 0.79 | AR (0.33) | — | |
| SCHEMBL7690601 | 0.77 | HSP90AB1 (0.39) | PDE2AUSP8USP7 | |
| SCHEMBL8031860 | 0.77 | HSD11B1 (0.40) | HSD11B1CRHR1ADORA2AADORA2BSLC34A1 | |
| SCHEMBL7694533 | 0.75 | NTRK1 (0.35) | L3MBTL1 | |
| SCHEMBL7968440 | 0.73 | — | — | |
| SCHEMBL7691483 | 0.73 | KDM1A (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339046-B1 | FOR CONTROLLING WEEDS | SYNGENTA INVESTMENT CORPORATION | 2002-01-15 | — | — | US | disclosed |
| EP-0839808-A1 | Pyrazole derivatives, processes for their preparation, and their use as herbicides | Novartis AG (CH) | 1998-05-06 | — | — | EP | disclosed |