Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696259 | 0.82 | NR1H4 (0.56) | NR1H4PPARGRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15292811 | 0.74 | FADS1 (0.55) | NR1H4PPARGRAB9AHPGDSTAT3 | |
| SCHEMBL13605105 | 0.73 | KCNK9 (0.70) | NR1H4PPARGRAB9ASTAT3NPC1 | |
| SCHEMBL13659673 | 0.73 | NPSR1 (0.69) | RAB9APOLBSTAT3NPC1SMN1; SMN2 | |
| SCHEMBL27453091 | 0.73 | ALDH1A1 (0.56) | RAB9ASTAT3NPC1SMN1; SMN2MAPT | |
| SCHEMBL7934460 | 0.72 | F2 (0.50) | RAB9APOLBHPGDMAPTMEN1 | |
| SCHEMBL3220462 | 0.72 | ABL1 (0.55) | RAB9APOLBSTAT3NPC1SMN1; SMN2 | |
| SCHEMBL13612623 | 0.72 | RAB9A (0.57) | NR1H4RAB9ASTAT3NPC1SMN1; SMN2 | |
| SCHEMBL27214421 | 0.72 | PPARG (0.57) | NR1H4PPARGPKMSTAT3SMN1; SMN2 | |
| SCHEMBL13662571 | 0.71 | L3MBTL1 (0.61) | RAB9APOLBHPGDNPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002053544-A1 | PHARMACEUTICAL USES AND SYNTHESIS OF NICOTINANILIDE-N-OXIDES | DARWIN DISCOVERY LTD. (GB) | 2002-07-11 | — | — | WO | disclosed |