Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.69 |
| ▸ | MMP2 | P08253 | 10/20 | 0.69 |
| ▸ | MMP3 | P08254 | 9/20 | 0.69 |
| ▸ | PDE4A | P27815 | 8/20 | 0.69 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.69 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.69 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.69 |
| ▸ | MMP13 | P45452 | 4/20 | 0.61 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7073256 | 0.86 | MMP2 (0.77) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6824624 | 0.82 | MMP2 (1.00) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6934585 | 0.81 | MMP1 (0.70) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL12268068 | 0.79 | MMP8 (0.47) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL7207040 | 0.79 | MMP1 (0.76) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL12268065 | 0.78 | MMP8 (0.46) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL7305191 | 0.78 | MMP1 (0.76) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6932995 | 0.77 | MMP1 (0.54) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL7212123 | 0.76 | MMP1 (1.00) | MMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6823613 | 0.76 | MMP2 (0.87) | MMP1MMP2MMP3PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342508-B1 | ENZYME INHIBITORS FOR PROTECTION OF CONNECTIVE TISSUES | AMERICAN CYANAMID COMPANY | 2002-01-29 | — | — | US | disclosed |