Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27514114 | 0.77 | CDC25A (0.42) | ALOX5OPRM1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL29158505 | 0.72 | ALDH1A1 (0.55) | ALOX5CES2MEN1KMT2AALDH1A1 | |
| SCHEMBL7815749 | 0.72 | AADAT (0.36) | MEN1KMT2AOPRM1OPRK1OPRL1 | |
| SCHEMBL31613810 | 0.72 | EGFR (0.50) | EP300CES2KDM4CMEN1KMT2A | |
| SCHEMBL5667766 | 0.72 | EGFR (0.50) | EP300CES2KDM4CMEN1KMT2A | |
| SCHEMBL30692063 | 0.72 | BCHE (0.46) | ALOX5EP300 | |
| SCHEMBL8797180 | 0.71 | KMT2A (0.47) | ALOX5EP300MEN1KMT2A | |
| SCHEMBL13489152 | 0.70 | EGFR (0.49) | EP300CES2KDM4CMEN1KMT2A | |
| SCHEMBL8273860 | 0.70 | AADAT (0.41) | OPRM1ALDH1A1 | |
| SCHEMBL4687956 | 0.70 | ALOX5 (0.50) | ALOX5EP300CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002038543-A2 | 3-SUBSTITUTED OXINDOLE BETA 3 AGONISTS | ELI LILLY AND COMPANY (US) | 2002-05-16 | — | — | WO | disclosed |