Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027686 | 0.76 | ALDH1A1 (0.39) | NR1I2 | |
| SCHEMBL9356958 | 0.73 | NR1I2 (0.40) | NR1I2 | |
| SCHEMBL7694915 | 0.71 | ESR1 (0.54) | — | |
| SCHEMBL7689050 | 0.70 | BCHE (0.40) | BCHEACHE | |
| SCHEMBL7695045 | 0.69 | BCHE (0.37) | BCHEACHE | |
| SCHEMBL8789363 | 0.67 | MAPK1 (0.36) | NR1I2 | |
| SCHEMBL9027574 | 0.67 | DRD2 (0.39) | — | |
| SCHEMBL8790260 | 0.66 | ESR1 (0.39) | NR1I2 | |
| SCHEMBL9029036 | 0.66 | TLR9 (0.41) | — | |
| SCHEMBL7692326 | 0.66 | ESR1 (0.43) | NR1I2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081444-A1 | 1-INDOLYL DERIVATIVES, USE THEREOF FOR PRODUCTION OF MEDICAMENTS, A METHOD FOR PRODUCTION OF SAID 1-INDOLYL DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING 1-INDOLYL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-10-17 | — | — | WO | disclosed |