Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692562 | 0.84 | L3MBTL1 (0.51) | KDM4EALDH1A1HDAC1 | |
| SCHEMBL7702285 | 0.84 | L3MBTL1 (0.51) | KDM4EALDH1A1HDAC1 | |
| SCHEMBL7693885 | 0.84 | L3MBTL1 (0.51) | KDM4EALDH1A1HDAC1 | |
| SCHEMBL7696748 | 0.84 | L3MBTL1 (0.51) | KDM4EALDH1A1HDAC1 | |
| SCHEMBL7703489 | 0.81 | DRD4 (0.47) | KDM4EALDH1A1HDAC1 | |
| SCHEMBL8413838 | 0.80 | ADRB2 (0.59) | KDM4EALDH1A1ADRB2NPSR1TDP1 | |
| SCHEMBL4749149 | 0.79 | NR5A1 (0.51) | — | |
| SCHEMBL4748690 | 0.79 | NR5A1 (0.51) | — | |
| SCHEMBL9699146 | 0.79 | NR5A1 (0.51) | — | |
| SCHEMBL4745433 | 0.79 | NR5A1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024619-A1 | AMINE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2002-03-28 | — | — | WO | disclosed |