Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | GLA | P06280 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | CASP7 | P55210 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.52 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzanthrone SCHEMBL27947469 | 0.89 | PABPC1 (0.72) | ALDH1A1HSD17B10MAPK1MAPTHPGD | |
| SCHEMBL1187919 | 0.86 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1MAPTHPGD | |
| Pyrene SCHEMBL28323778 | 0.84 | ALDH1A1 (0.75) | ALDH1A1HSD17B10MAPK1MAPTHPGD | |
| Fluoranthene SCHEMBL7921020 | 0.84 | ALDH1A1 (0.83) | ALDH1A1HSD17B10MAPK1MAPTHPGD | |
| Pyrene SCHEMBL27621475 | 0.82 | ALDH1A1 (0.71) | ALDH1A1HSD17B10MAPTHPGDTSHR | |
| SCHEMBL14541683 | 0.82 | RAB9A (0.58) | ALDH1A1HSD17B10MAPK1MAPTHPGD | |
| SCHEMBL23525587 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPK1MAPTHPGD | |
| Fluoranthene SCHEMBL8873541 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPK1MAPTHPGD | |
| Acridine SCHEMBL29352289 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGLAL3MBTL1 | |
| Acridine SCHEMBL1772714 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344654-B1 | AN ETHYLENICALLY UNSATURATED MONOMER IS COPOLYMERIZED WITH A POLYNUCLEAR AROMATIC HYDROCARBON OR A SUBSTITUTED AROMATIC DERIVATIVE THEREOF, SUCH THAT THE RESULTANT POLYMER IS FLUORESCENT. | ROHM AND HAAS COMPANY | 2002-02-05 | — | — | US | claimed |