Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27151512 | 0.78 | MEN1 (0.33) | KMT2AMEN1TMEM97SIGMAR1HCRTR2 | |
| SCHEMBL7695040 | 0.75 | PDE4D (0.36) | — | |
| SCHEMBL15398143 | 0.74 | CA2 (0.33) | YWHAZ | |
| SCHEMBL7695216 | 0.74 | SYNJ2 (0.35) | ALDH1A1YWHAZ | |
| SCHEMBL21077799 | 0.70 | MEN1 (0.33) | KMT2AMEN1TMEM97SIGMAR1HCRTR2 | |
| SCHEMBL7154934 | 0.70 | MEN1 (0.41) | KMT2AMEN1TMEM97SIGMAR1YWHAZ | |
| SCHEMBL19243948 | 0.69 | TMEM97 (0.30) | TMEM97SIGMAR1 | |
| SCHEMBL17227613 | 0.69 | TMEM97 (0.30) | TMEM97SIGMAR1 | |
| SCHEMBL12944600 | 0.68 | ALDH1A1 (0.35) | ALDH1A1KDM4EKMT2AMEN1TP53 | |
| SCHEMBL6567769 | 0.68 | L3MBTL1 (0.39) | KMT2AMEN1TMEM97SIGMAR1YWHAZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335458-B1 | COMPOUNDS CORRESPONDING TO A RING PART OF VITAMIN D DERIVATIVES HAVING 3-HYDROXYPROPYLOXY GROUP AT 2 BETA-POSITION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-01-01 | — | — | US | disclosed |
| EP-1072582-A1 | INTERMEDIATE COMPOUNDS IN THE SYNTHESIS OF THE A RING MOIETY OF 2-SUBSTITUTED VITAMIN D DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-01-31 | — | — | EP | disclosed |