Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702181 | 0.95 | MEN1 (0.44) | ALDH1A1LMNAMAPTMAPK1GAA | |
| SCHEMBL7700006 | 0.94 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1GAA | |
| SCHEMBL7693979 | 0.85 | IKBKB (0.42) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL7699962 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1GAA | |
| SCHEMBL7699627 | 0.84 | IKBKB (0.40) | ALDH1A1MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL7699727 | 0.81 | IKBKB (0.42) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL7695326 | 0.81 | IKBKB (0.40) | ALDH1A1MAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL7693910 | 0.81 | NPC1 (0.45) | HTTSMN1; SMN2KDM4EHSD17B10GFER | |
| SCHEMBL7698726 | 0.81 | LMNA (0.47) | LMNAMAPTMAPK1POLB | |
| SCHEMBL7701455 | 0.80 | NAMPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |