Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693979 | 0.91 | IKBKB (0.42) | IKBKBKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL7700674 | 0.87 | RAB9A (0.42) | RAB9AALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL7698726 | 0.85 | LMNA (0.47) | IKBKBRAB9AMAPTPOLB | |
| SCHEMBL7695326 | 0.85 | IKBKB (0.40) | IKBKBRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7702181 | 0.85 | MEN1 (0.44) | IKBKBKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7698091 | 0.85 | HTT (0.46) | NPC1ALDH1A1MAPTHPGDHTT | |
| SCHEMBL7696445 | 0.84 | ALDH1A1 (0.46) | KMT2ASMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL7700006 | 0.83 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2ALDH1A1MEN1MAPT | |
| SCHEMBL7699216 | 0.83 | IKBKB (0.41) | IKBKBKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL7695157 | 0.82 | IKBKB (0.48) | IKBKBRAB9AKMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |