Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700006 | 0.91 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNAHTTGAA | |
| SCHEMBL7696445 | 0.84 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAHTTGAA | |
| SCHEMBL7703035 | 0.80 | MAPT (0.50) | ALDH1A1SMN1; SMN2LMNAHTTGAA | |
| SCHEMBL7702181 | 0.79 | MEN1 (0.44) | ALDH1A1SMN1; SMN2LMNAHTTGAA | |
| SCHEMBL7695335 | 0.77 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2LMNAMAPTMAPK1 | |
| SCHEMBL29158637 | 0.77 | HPGD (0.45) | ALDH1A1SMN1; SMN2LMNAHTTGAA | |
| SCHEMBL30106384 | 0.77 | USP2 (0.45) | ALDH1A1LMNAHTTTSHR | |
| SCHEMBL7701183 | 0.76 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2LMNAHTTGAA | |
| SCHEMBL13762069 | 0.75 | ALDH1A1 (0.82) | ALDH1A1SMN1; SMN2LMNAHTTGAA | |
| SCHEMBL7695145 | 0.74 | IKBKB (0.45) | ALDH1A1LMNAHTTMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |