Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 4/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696445 | 0.95 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1AVPR1BKDM4E | |
| SCHEMBL7700006 | 0.89 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL7693979 | 0.87 | IKBKB (0.42) | MEN1KMT2AERN1ALDH1A1HDAC3 | |
| SCHEMBL7699627 | 0.85 | IKBKB (0.40) | MEN1KMT2AALDH1A1HDAC3HDAC4 | |
| SCHEMBL7699727 | 0.82 | IKBKB (0.42) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7698726 | 0.82 | LMNA (0.47) | MAPTLMNAMAPK1IKBKB | |
| SCHEMBL7693910 | 0.82 | NPC1 (0.45) | ERN1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL7695326 | 0.82 | IKBKB (0.40) | ALDH1A1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29158637 | 0.82 | HPGD (0.45) | MEN1KMT2AALDH1A1HDAC2HDAC8 | |
| SCHEMBL7705228 | 0.81 | SMN1; SMN2 (0.56) | MEN1KMT2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |