Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.79 |
| ▸ | PKM | P14618 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | GUSB | P08236 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | DHFR | P00374 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 2/20 | 0.63 |
| ▸ | CA2 | P00918 | 2/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695444 | 0.89 | ALDH1A1 (1.00) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL7689428 | 0.88 | ADORA2B (0.78) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL3003016 | 0.86 | PKM (1.00) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL19752673 | 0.86 | PKM (1.00) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL16792165 | 0.83 | ALDH1A1 (0.78) | ALDH1A1ADORA2BKMT2ATDP1ALOX12 | |
| SCHEMBL7690389 | 0.80 | DHFR (1.00) | ALDH1A1ADORA2BKMT2AALOX12GUSB | |
| SCHEMBL1666306 | 0.79 | ALDH1A1 (0.74) | ALDH1A1ADORA2BKMT2APKMMAPT | |
| SCHEMBL10113419 | 0.78 | CA1 (1.00) | ALDH1A1ADORA2BKMT2AALOX12POLB | |
| SCHEMBL28558189 | 0.77 | DHFR (0.81) | ALDH1A1ADORA2BKMT2AALOX12POLB | |
| SCHEMBL7691449 | 0.77 | ADORA2B (1.00) | ALDH1A1ADORA2BKMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | claimed |
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |