Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 6/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 6/20 | 0.42 |
| ▸ | MMP13 | P45452 | 6/20 | 0.42 |
| ▸ | MMP8 | P22894 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14935456 | 0.86 | MMP9 (0.45) | MMP9ADAM17MMP2MMP13MMP8 | |
| SCHEMBL4174555 | 0.85 | CYP3A4 (0.49) | MMP9ADAM17MMP2MMP13MMP8 | |
| SCHEMBL6692258 | 0.79 | ADAMTS5 (0.35) | ADAM17MMP2MMP13ALDH1A1CACNA1F | |
| SCHEMBL27952144 | 0.77 | MMP9 (0.58) | MMP9ADAM17MMP2MMP13MMP8 | |
| SCHEMBL7097777 | 0.75 | ALDH1A1 (0.60) | MMP9ADAM17MMP2MMP13MMP8 | |
| SCHEMBL15972776 | 0.75 | ALDH1A1 (0.60) | MMP9ADAM17MMP2MMP13MMP8 | |
| SCHEMBL6693034 | 0.74 | LMNA (0.40) | ADAM17MMP2MMP13ALDH1A1CYP3A4 | |
| SCHEMBL4618724 | 0.73 | ADAMTS5 (0.35) | ADAM17MMP2MMP13ALDH1A1CYP3A4 | |
| SCHEMBL11598474 | 0.73 | ALDH1A1 (0.33) | ADAM17MMP2MMP13ALDH1A1CACNA1F | |
| SCHEMBL6692728 | 0.71 | PDE7A (0.40) | MMP9ADAM17MMP2MMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | disclosed |