Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL28467152 | 0.80 | CES2 (0.45) | MEN1KMT2ACES2CES1CYP3A4 | |
| Morpholine SCHEMBL4270671 | 0.79 | ACHE (0.54) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Toluene SCHEMBL3946837 | 0.78 | LMNA (0.50) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Fluoride SCHEMBL7653631 | 0.76 | CES2 (0.59) | MEN1KMT2ACES2CES1DRD2 | |
| Fluoride SCHEMBL27260103 | 0.76 | — | — | |
| Morpholine SCHEMBL27991007 | 0.76 | CYP2A6 (0.61) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28321548 | 0.76 | ADRB1 (0.41) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL27881753 | 0.76 | ACHE (0.58) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL6137775 | 0.75 | MEN1 (0.44) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28439560 | 0.75 | CYP2A6 (0.59) | MEN1KMT2AKDM4EGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002048160-A1 | STERICALLY HINDERED PHOSPHINE LIGANDS AND USES THEREOF | YALE UNIVERSITY (US) | 2002-06-20 | — | — | WO | disclosed |