Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.36 |
| ▸ | TUBB | P07437 | 7/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7693551 | 0.86 | MDM4 (0.38) | PDE10ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7694116 | 0.84 | PDE10A (0.42) | PDE10ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7697885 | 0.76 | MTNR1A (0.44) | PDE10ATRPC5KDM4EMTNR1AMTNR1B | |
| SCHEMBL7699984 | 0.72 | TRPC5 (0.42) | PDE10ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7693001 | 0.69 | AKR1C2 (0.49) | PDE10ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17501698 | 0.68 | KDM4E (0.46) | PDE10ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6302778 | 0.68 | TUBB4A (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7274263 | 0.67 | POLB (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7699488 | 0.66 | ALDH1A1 (0.50) | TRPC5MTNR1AMTNR1B | |
| SCHEMBL27669225 | 0.65 | ALDH1A1 (0.41) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020478-A1 | N-BENZYLINDOLE-3-ACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DRUG RESISTAN CANCER | DUBLIN CITY UNIVERSITY (IE) | 2002-03-14 | — | — | WO | claimed |
| WO-2002020478-A1 | N-BENZYLINDOLE-3-ACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DRUG RESISTAN CANCER | DUBLIN CITY UNIVERSITY (IE) | 2002-03-14 | — | — | WO | disclosed |