Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27654815 | 0.98 | KDM4E (0.45) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| SCHEMBL81238 | 0.91 | KDM4E (0.54) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Hydrogen Sulfide SCHEMBL5998579 | 0.91 | KDM4E (0.54) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Benzene SCHEMBL29130108 | 0.91 | KDM4E (0.54) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Bromide SCHEMBL653934 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Hydrochloric Acid SCHEMBL80718 | 0.89 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Bromide SCHEMBL117943 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| SCHEMBL990633 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| Hydrochloric Acid SCHEMBL7263491 | 0.89 | KDM4E (0.58) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 | |
| SCHEMBL11224727 | 0.89 | KDM4E (0.52) | KDM4EALDH1A1TDP1CYP1A2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246108-A1 | Method for Producing Alpha-Azidoaniline Derivative or Alpha,AlphaPrime-Diazide Derivative | TOKUYAMA CORPORATION (JP) | 2021-08-12 | — | — | US | claimed |
| EP-3816151-A1 | METHOD FOR PRODUCING ?-AZIDOANILINE DERIVATIVE OR ?, ?'-DIAZIDE DERIVATIVE | Tokuyama Corporation (JP) | 2021-05-05 | — | — | EP | claimed |
| CN-112262124-A | Process for producing alpha-azidoaniline derivative or alpha, alpha' -diazide derivative | 株式会社德山 | 2021-01-22 | — | — | CN | claimed |
| EP-1644395-B1 | PROCESSES FOR PREPARING 4'AZIDO NUCLEOSIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-11-22 | — | — | EP | claimed |
| EP-1644395-A1 | PROCESSES FOR PREPARING 4'AZIDO NUCLEOSIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-04-12 | — | — | EP | claimed |
| US-20050038240-A1 | Processes for preparing 4'-azido-nucleoside derivatives | ROCHE PALO ALTO LLC | 2005-02-17 | — | — | US | claimed |
| WO-2005000864-A1 | PROCESSES FOR PREPARING 4’AZIDO NUCLEOSIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-06 | — | — | WO | claimed |
| CN-117509571-A | Method for continuously preparing iodine azide and application thereof | 乐威医药（江苏）股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| US-20210246108-A1 | Method for Producing Alpha-Azidoaniline Derivative or Alpha,AlphaPrime-Diazide Derivative | TOKUYAMA CORPORATION (JP) | 2021-08-12 | — | — | US | disclosed |
| EP-3816151-A1 | METHOD FOR PRODUCING ?-AZIDOANILINE DERIVATIVE OR ?, ?'-DIAZIDE DERIVATIVE | Tokuyama Corporation (JP) | 2021-05-05 | — | — | EP | disclosed |
| CN-112262124-A | Process for producing alpha-azidoaniline derivative or alpha, alpha' -diazide derivative | 株式会社德山 | 2021-01-22 | — | — | CN | disclosed |
| EP-2619215-B1 | AZIDO NUCLEOSIDES AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA INC (US) | 2018-09-05 | — | — | EP | disclosed |
| EP-2752422-B1 | Stereoselective synthesis of phosphorus containing actives | GILEAD PHARMASSET LLC (US) | 2017-08-16 | — | — | EP | disclosed |
| US-20110245484-A1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS CONTAINING ACTIVES | PHARMASSET, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| EP-1644395-B1 | PROCESSES FOR PREPARING 4'AZIDO NUCLEOSIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-11-22 | — | — | EP | disclosed |
| EP-1644395-A1 | PROCESSES FOR PREPARING 4'AZIDO NUCLEOSIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-04-12 | — | — | EP | disclosed |
| US-20050038240-A1 | Processes for preparing 4'-azido-nucleoside derivatives | ROCHE PALO ALTO LLC | 2005-02-17 | — | — | US | disclosed |
| WO-2005000864-A1 | PROCESSES FOR PREPARING 4’AZIDO NUCLEOSIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-01-06 | — | — | WO | disclosed |
| EP-0453642-A1 | Glycidyl azide polymer (gap) synthesis by molten salt method | ROCKWELL INTERNATIONAL CORPORATION (US) | 1991-10-30 | — | — | EP | disclosed |
| US-5055600-A | Azide treatment of polyepichlorohydrin with quaternary ammonium azide ions | ROCKWELL INTERNATIONAL CORPORATION (US) | 1991-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038240-A1 | Processes for preparing 4'-azido-nucleoside derivatives | NUDT1, RNGTT, DUT | KDM4E 3974/4885ALDH1A1 920/4885TDP1 1725/4885 |
| US-20110245484-A1 | STEREOSELECTIVE SYNTHESIS OF PHOSPHORUS CONTAINING ACTIVES | PPA1, ENPP1, ITPA | KDM4E 4417/4885ALDH1A1 2383/4885TDP1 2182/4885 |
| US-20210246108-A1 | Method for Producing Alpha-Azidoaniline Derivative or Alpha,AlphaPrime-Diazide Derivative | QDPR, AZI2, NISCH | KDM4E 4043/4885ALDH1A1 50/4885TDP1 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.