Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695589 | 0.77 | APP (0.46) | SMN1; SMN2ALDH1A1HPGDNQO2KDM4E | |
| SCHEMBL7697058 | 0.76 | RAB9A (0.50) | SMN1; SMN2ALDH1A1NQO2LMNAL3MBTL1 | |
| SCHEMBL7694614 | 0.76 | HTR7 (0.40) | SMN1; SMN2ALDH1A1NQO2LMNAMAPK1 | |
| SCHEMBL7699341 | 0.73 | LMNA (0.45) | SMN1; SMN2ALDH1A1HPGDNQO2KDM4E | |
| SCHEMBL7692496 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HPGDNQO2KDM4E | |
| SCHEMBL7698454 | 0.72 | NQO2 (0.45) | SMN1; SMN2ALDH1A1NQO2LMNAMAPK1 | |
| SCHEMBL3888294 | 0.72 | L3MBTL1 (0.55) | SMN1; SMN2ALDH1A1RECQLL3MBTL1MTNR1A | |
| SCHEMBL2284298 | 0.70 | MTNR1A (0.62) | ALDH1A1MAPK1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL30753695 | 0.70 | MTNR1A (0.62) | ALDH1A1MAPK1L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL11363528 | 0.70 | L3MBTL1 (0.47) | SMN1; SMN2ALDH1A1LMNAL3MBTL1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |