Oteracil

Oteracil

SCHEMBL7697987

O=C(O)c1nc(O)nc(O)n1

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.32
TSHR P16473 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1146219 0.79 TSHR (0.38) ALOX15TSHRKDM4EACMSDTDP1
Hydrochloric Acid SCHEMBL2032392 0.76 TSHR (0.36) ALOX15TSHRKDM4EACMSDTDP1
Potassium SCHEMBL30932480 0.76 TSHR (0.36) ALOX15TSHRKDM4EACMSDTDP1
SCHEMBL29223372 0.76 TSHR (0.36) ALOX15TSHRKDM4EACMSDTDP1
SCHEMBL11322870 0.73
SCHEMBL8109492 0.71 KMO (0.35) ALOX15TSHRKDM4EACMSDTDP1
SCHEMBL944176 0.71 ALOX15 (0.39) ALOX15TSHRKDM4EACMSDTDP1
Urea SCHEMBL400230 0.69 LMNA (0.46) ALOX15TDP1
SCHEMBL7696671 0.67 KMO (0.32) ALOX15TSHRKDM4EACMSDTDP1
SCHEMBL7692962 0.67 TSHR (0.47) ALOX15TSHRKDM4EACMSDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1294682-A Compsn. and method for hemoglobin and cell analysis COULTER INT CORP (US) 2001-05-09 CN claimed
CN-1244259-A A cyanide-free lytic reagent compositiona nd method for hemoglobin and cell analysis COULTER INT CORP (US) 2000-02-09 CN claimed
US-10266737-B2 Adsorption systems using metal-organic frameworks ARKEMA INC. (US) 2019-04-23 US disclosed
US-20150291870-A1 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS ARKEMA INC. 2015-10-15 US disclosed
EP-2885365-A2 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS Arkema, Inc. (US) 2015-06-24 EP disclosed
WO-2014028574-A9 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS ARKEMA INC. (US) 2015-04-02 WO disclosed
WO-2014028574-A2 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS ARKEMA INC. (US) 2014-02-20 WO disclosed
CN-102662067-A Cyanide-free hemolysin for determining hemoglobin concentration and carrying out white blood cell count by groups YANTAI EXCELLENT BIOTECHNOLOGY CO LTD 2012-09-12 CN disclosed
WO-2009083553-A1 AZINE COMPOUNDS AS GLUCOKINASE ACTIVATORS RHEOSCIENCE A/S (DK) 2009-07-09 WO disclosed
CN-1154848-C A cyanide-free lytic reagent compositiona nd method for hemoglobin and cell analysis ���ع��ʹ�˾ 2004-06-23 CN disclosed
CN-1153972-C Compsn. and method for hemoglobin and cell analysis 库特国际公司 2004-06-16 CN disclosed
US-6337368-B1 WATER INSOLUBLE CARRIERS WITH P-NITROBENZOIC ACID, AROMATIC AMINES, AMIDES, SULFONAMIDES AND HYDRAZIDES KANEKA CORPORATION (JP) 2002-01-08 US disclosed
CN-1294682-A Compsn. and method for hemoglobin and cell analysis COULTER INT CORP (US) 2001-05-09 CN disclosed
CN-1244259-A A cyanide-free lytic reagent compositiona nd method for hemoglobin and cell analysis COULTER INT CORP (US) 2000-02-09 CN disclosed
EP-0003817-B1 ANTI-CORROSIVE PAINTS Henkel Kommanditgesellschaft auf Aktien (DE) 1981-02-11 EP disclosed
US-4213986-A DERIVATIVES CONTAIN TETRAZOLE RING, TREATMENT OF PURINE METABOLIC DISORDER, ANTIURICOPATHIC HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-22 US disclosed
US-4152440-A DIURETICS, ANALGESICS HOECHST AKTIENGESELLSCHAFT (DE) 1979-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291870-A1 ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS PFAS, CHIA, PARN ALOX15 2929/4885TSHR 4470/4885KDM4E 1450/4885
US-10266737-B2 Adsorption systems using metal-organic frameworks PFAS, CHIA, PARN ALOX15 2929/4885TSHR 4470/4885KDM4E 1450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.