Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.34 |
| ▸ | FNTB | P49356 | 5/20 | 0.34 |
| ▸ | MCOLN2 | Q8IZK6 | 2/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705532 | 0.85 | HHAT (0.37) | PRCP | |
| SCHEMBL7705677 | 0.85 | HHAT (0.37) | PRCP | |
| SCHEMBL7698066 | 0.83 | TRPM5 (0.40) | FNTAFNTBPTAFR | |
| SCHEMBL7705565 | 0.83 | CHRM3 (0.35) | FNTAFNTBPRCP | |
| SCHEMBL7705666 | 0.82 | GAA (0.36) | PRCP | |
| SCHEMBL7705731 | 0.80 | TRPM8 (0.36) | PRCP | |
| SCHEMBL7704956 | 0.79 | CHRM3 (0.47) | PRCP | |
| SCHEMBL7703410 | 0.78 | PRCP (0.35) | PRCP | |
| SCHEMBL7701032 | 0.76 | HPGD (0.37) | PRCP | |
| SCHEMBL7698116 | 0.76 | TRPM8 (0.45) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901488-B1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-11-06 | — | — | EP | disclosed |
| EP-0901488-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043277-A1 | 2,4-DIAMINOPYRIMIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-11-20 | — | — | WO | disclosed |