Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593785 | 0.71 | NOTUM (0.42) | — | |
| SCHEMBL18939799 | 0.66 | AKR1C3 (0.42) | LMNAPTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL14896280 | 0.65 | OXER1 (0.40) | LMNA | |
| SCHEMBL4047206 | 0.64 | NOTUM (0.54) | LMNAPTGS2PTGS1AKR1C3AKR1C2 | |
| SCHEMBL3223413 | 0.64 | PTGS2 (0.43) | LMNAPTGS2PTGDR2PTGS1 | |
| SCHEMBL11330088 | 0.63 | LMNA (0.59) | LMNAPTGS2AKR1C3AKR1C2 | |
| SCHEMBL7284268 | 0.62 | POLB (0.48) | LMNA | |
| SCHEMBL5564634 | 0.62 | ALDH1A1 (0.60) | PTGS1 | |
| SCHEMBL19778027 | 0.62 | KMT2A (0.54) | PTGDR2AKR1C3AKR1C2 | |
| SCHEMBL22831319 | 0.62 | NOTUM (0.44) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068394-A1 | QUINOLINE DERIVATIVE AS TYROSINE KINASE INHIBITOR | GLAXO GROUP LIMITED (GB) | 2002-09-06 | — | — | WO | disclosed |