Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 6/20 | 0.38 |
| ▸ | KLK7 | P49862 | 5/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703661 | 1.00 | AGTR2 (0.38) | AGTR2KLK7STSGPR119KLK5 | |
| SCHEMBL31486428 | 0.81 | KLK7 (0.49) | KLK7STSKLK5PRSS1PRSS2 | |
| SCHEMBL8669568 | 0.81 | KLK7 (0.49) | KLK7STSKLK5PRSS1PRSS2 | |
| SCHEMBL5065670 | 0.81 | KLK7 (0.49) | KLK7STSKLK5PRSS1PRSS2 | |
| SCHEMBL7698258 | 0.81 | HSD17B10 (0.33) | KLK7STSKDM4E | |
| SCHEMBL7698260 | 0.81 | HSD17B10 (0.33) | KLK7STSKDM4E | |
| SCHEMBL6494880 | 0.78 | KLK7 (0.36) | KLK7KLK5KDM4EPRSS1PRSS2 | |
| SCHEMBL7699900 | 0.78 | KLK7 (0.43) | KLK7STSGPR119KLK5KDM4E | |
| SCHEMBL7790063 | 0.77 | FKBP1A (0.41) | KLK7 | |
| SCHEMBL7790201 | 0.77 | FKBP1A (0.40) | KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014261-A2 | 4-SUBSTITUTED D-GLUTAMIC ACID DERIVATIVES FOR USE AS ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |