Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | FADS1 | O60427 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24210299 | 0.81 | KEAP1 (0.63) | KEAP1FADS1HDAC1CES2CES1 | |
| SCHEMBL7698452 | 0.77 | NOS2 (0.48) | HDAC1ALDH1A1BRAF | |
| SCHEMBL1559256 | 0.77 | KEAP1 (0.58) | KEAP1FADS1HDAC1CES2CES1 | |
| SCHEMBL690577 | 0.76 | KEAP1 (0.61) | KEAP1FADS1HDAC1CES2CES1 | |
| SCHEMBL29520286 | 0.75 | KEAP1 (0.56) | KEAP1FADS1HDAC1CES2CES1 | |
| SCHEMBL13753884 | 0.75 | KEAP1 (0.56) | KEAP1FADS1HDAC1CES2CES1 | |
| SCHEMBL15630978 | 0.74 | KEAP1 (0.59) | KEAP1FADS1HDAC1HDAC3HDAC2 | |
| SCHEMBL11575893 | 0.73 | KEAP1 (0.58) | KEAP1FADS1HDAC1CES2CES1 | |
| SCHEMBL4333053 | 0.72 | KEAP1 (0.56) | KEAP1FADS1HDAC1ALDH1A1BRAF | |
| SCHEMBL135091 | 0.71 | KEAP1 (1.00) | KEAP1FADS1HDAC1PYGLCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |